Biocommunication and natural genome editing

Biocommunication and natural genome editing.

The biocommunicative approach investigates communication processes within and among cells, tissues, organs and organisms as sign-mediated interactions, and nucleotide sequences as code, i.e. language-like text, which follows in parallel three kinds of rules: combinatorial (syntactic), context-sensitive (pragmatic), and content-specific (semantic). Natural genome editing from a biocommunicative ...

Advancing Chimeric Antigen Receptor-Engineered T-Cell Immunotherapy Using Genome Editing Technologies: Challenges and Future Prospects

Chimeric antigen receptor engineered-T (CAR-T) cells also named as living drugs, have been recently known as a breakthrough technology and were applied as an adoptive immunotherapy against different types of cancer. They also attracted widespread interest because of the success of B-cell malignancy therapy achieved by anti-CD19 CAR-T cells. Current genetic toolbox enabled the synthesis of CARs ...

Bioenergetics and Biocommunication

1. Introduction 2. Energy storage frees the organism from thermodynamic constraints Energy storage and mobilization in living systems Thermodynamics of the steady state vs thermodynamics of organized complexity The living system is free from immediate thermodynamic constraints 3. The exquisite sensitivity of organisms Energy self-sufficiency and sensitivity The polychromatic whole 4. The interc...

Genome Editing



NATURAL GENETIC ENGINEERING AND NATURAL GENOME EDITING Revisiting the Central Dogma in the 21st Century

Since the elaboration of the central dogma of molecular biology, our understanding of cell function and genome action has benefited from many radical discoveries. The discoveries relate to interactive multimolecular execution of cell processes, the modular organization of macromolecules and genomes, the hierarchical operation of cellular control regimes, and the realization that genetic change ...